Bioinformatician neoantigen peptide-based cancer vaccines

Company: Erasmus MC-Klinische Chemie

  • Location: Rotterdam, Netherlands
  • Employment type: Full-time
  • Posted: Yesterday
  • Offer language: English

Job description

Job Description

Within the Department of Pulmonary Medicine, we are seeking a highly motivated and enthusiastic bioinformatician who will join us in developing neoantigen peptide-based cancer vaccines for the treatment of pancreatic cancer patients.

Your Main Tasks Will Include

  • Develop and maintain a bioinformatics pipeline for neoantigen identification.
  • Analyze next-generation sequencing data (WES, RNA-seq) to identify tumor-specific mutations.
  • Implement and optimize machine learning algorithms for neoantigen prediction.
  • Integrate public and proprietary datasets to improve pipeline accuracy.
  • Collaborate with wet-lab scientists to validate predicted neoantigens.
  • Maintain and document computational workflows to ensure reproducibility.
  • Contribute to research publications and grant applications.

For candidates interested in pursuing a PhD, this position may provide an opportunity to develop into a PhD trajectory, depending on the candidate’s ambitions and performance, project progress, and funding availability.

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