Clinical Research Associate II

CRA II - Netherlands

Remote | Dedicated Sponsor Model | Global CRO | Bonus Scheme

Build long-term sponsor expertise while accelerating your CRA career.

We're partnering with a leading global CRO to appoint a CRA II to join their established Clinical Operations team in the Netherlands.

This opportunity offers the best of both worlds, allowing you to become fully embedded within a dedicated sponsor environment while still benefiting from the structure, stability and career development opportunities of a global CRO.

You'll play a key role in managing investigative sites across the country, supporting study delivery from initiation through close-out and acting as a trusted partner to investigators and site personnel.

The organisation has built an excellent reputation for developing talent, offering structured progression plans, dedicated mentoring and multiple advancement opportunities within Clinical Operations.

What Makes This Different?

This isn't a traditional CRO monitoring role.

You'll be dedicated to a single sponsor, allowing you to develop deeper study knowledge, stronger site relationships and greater visibility within the sponsor organisation. Rather than constantly moving between different sponsors and processes, you'll gain the opportunity to become a true extension of the sponsor's study team.

After 12 months, you'll have the flexibility to either remain with your current sponsor or broaden your experience by moving into another sponsor partnership.

The business also offers a structured mentorship programme, an embedded CRO manager for ongoing support, and clearly defined progression frameworks with multiple career development steps, helping ambitious CRAs progress more quickly than is often possible within traditional clinical operations structures.

Combined with a collaborative local team environment, annual bonus scheme and strong internal mobility opportunities, this is an excellent platform for a CRA looking to accelerate their long-term career.

Why Join?

• Dedicated sponsor assignment
• Opportunity to rotate sponsors after 12 months
• Annual performance bonus
• Company car or car allowance
• Structured mentoring programme
• Embedded CRO management support
• Excellent internal career progression opportunities
• Multiple promotion levels
• Strong local team culture
• Home office support package
• Comprehensive healthcare and insurance benefits
• Exposure to a broad range of therapeutic areas, including Oncology studies

Role Overview

As a CRA II, you will be responsible for managing investigative sites throughout the clinical trial lifecycle, ensuring studies are conducted in line with protocol requirements, ICH-GCP guidelines and applicable regulations.

You will act as the primary point of contact for assigned sites, supporting investigators and site personnel while ensuring the quality, integrity and compliance of study data.

Working closely with project teams, you'll contribute to successful study delivery while building strong site relationships and supporting patient-focused clinical research.

Key Responsibilities

• Conduct site qualification, feasibility, initiation, routine monitoring and close-out visits across assigned studies.
• Evaluate site suitability and support investigator recruitment activities.
• Ensure study conduct remains compliant with protocol, regulatory requirements and ICH-GCP standards.
• Perform source data verification (SDV) and source data review (SDR) activities to ensure data accuracy and integrity.
• Monitor enrolment performance and identify potential recruitment risks.
• Review informed consent documentation and patient protection procedures.
• Support sites with protocol implementation and study-specific training.
• Verify investigational product accountability, storage conditions and reconciliation activities.
• Review essential study documentation to ensure inspection readiness.
• Resolve data queries through collaboration with site personnel and study teams.
• Produce accurate monitoring reports and follow-up correspondence within required timelines.
• Build effective working relationships with investigators, study coordinators and wider study stakeholders.
• Participate in investigator meetings, project meetings and sponsor interactions as required.
• Ensure all study deliverables are completed within agreed timelines and quality standards.

Experience & Requirements

• Previous independent monitoring experience within a CRO, FSP or sponsor environment.
• Experience conducting monitoring visits across the clinical trial lifecycle.
• Strong understanding of ICH-GCP guidelines and clinical trial regulations.
• Experience with SDV, SDR and query management activities.
• Ability to manage multiple sites and priorities simultaneously.
• Excellent communication and stakeholder management skills.
• Strong organisational and problem-solving capabilities.
• Comfortable working independently while contributing effectively to matrix study teams.
• Fluent Dutch and English language skills.
• Oncology experience would be advantageous but is not essential.
• Full driving licence and willingness to travel throughout the Netherlands as required.