Senior Clinical Trial Manager

Clinical Research Manager – CNS / Psychiatry & Multi-Specialty Trials

Location: West Palm Beach, FL | Full-Time | On-Site

Florida-Based Candidates Only | Hands-On Leadership | Recruitment & Operational Excellence

About Us

Health Synergy Clinical Research is a rapidly growing, multi-specialty clinical research organization conducting Phase I–IV trials, with a strong focus on schizophrenia, bipolar disorder, depression, dementia, Alzheimer's disease, and other CNS indications, alongside additional medical specialties.

We are seeking a highly motivated, detail-oriented, and results-driven Clinical Research Manager who can take ownership of patient recruitment, study execution, data quality, and team performance while building strong relationships with pharmaceutical sponsors and CROs.

This is not an administrative-only position. We need a hands-on leader who is comfortable working directly with complex patient populations, managing recruiters and coordinators, resolving operational challenges, and ensuring that studies progress efficiently from recruitment through randomization and data completion.

Key Responsibilities

1. Patient Recruitment, Engagement & Randomization

• Drive patient recruitment and enrollment, particularly for schizophrenia, bipolar disorder, dementia, Alzheimer's disease, and other CNS clinical trials.
• Understand the unique challenges of identifying, engaging, and retaining patients with serious psychiatric illnesses and cognitive impairment.
• Demonstrate exceptional interpersonal skills, empathy, patience, and the ability to build trust with patients, caregivers, and families.
• Use effective communication and de-escalation techniques when interacting with patients experiencing behavioral or psychiatric symptoms.
• Personally participate in recruitment and collaborate closely with dedicated recruiters, establishing clear goals, monitoring performance, and holding teams accountable.
• Develop practical recruitment strategies, improve prescreening and screening efficiency, and maximize appropriate randomization opportunities.
• Clearly explain study participation, address patient and caregiver concerns, and support voluntary, informed decision-making.
• Monitor recruitment pipelines, screen failures, enrollment timelines, and retention, proactively addressing barriers to study progress.

2. Clinical Trial Operations & Data Quality

• Take ownership of day-to-day trial execution across multiple active studies.
• Maintain exceptional attention to detail in protocol compliance, source documentation, EDC entry, and study procedures.
• Proactively identify potential protocol deviations, eligibility concerns, missing assessments, and documentation discrepancies before they become significant issues.
• Oversee timely and accurate EDC query responses, data reconciliation, and resolution of outstanding study action items.
• Regularly review patient charts, visit schedules, data quality, and trial progress to ensure operational accuracy.
• Maintain continuous audit and inspection readiness through organized documentation, internal quality reviews, and effective corrective and preventive actions.
• Protect patient safety, data integrity, and the site's regulatory compliance through diligent oversight and early problem identification.

3. Sponsor, CRO & CRA Relationships

• Serve as a confident, articulate, and knowledgeable point of contact for sponsors, CROs, and Clinical Research Associates (CRAs).
• Communicate clearly, professionally, and diplomatically during monitoring visits, sponsor meetings, audits, and operational discussions.
• Demonstrate a thorough understanding of study protocols, recruitment performance, patient progress, and data status.
• Anticipate monitoring concerns, resolve findings promptly, and maintain strong documentation supporting site compliance.
• Build lasting sponsor and CRO relationships through responsiveness, transparency, reliable execution, and consistent high-quality performance.
• Strengthen the site's reputation as a dependable research partner, contributing to repeat study opportunities and future trial acquisition.

4. Team Leadership, Accountability & Growth

• Lead and support clinical research coordinators, recruiters, and other research personnel.
• Establish clear performance expectations for recruitment, randomization, visit completion, query resolution, and documentation quality.
• Work collaboratively across clinical, recruitment, regulatory, and data teams to maintain efficient study execution.
• Provide hands-on coaching, identify performance gaps, and implement practical improvements.
• Demonstrate a growth mindset, continuously identifying opportunities to improve recruitment, strengthen operations, increase study capacity, and support organizational expansion.
• Take initiative, solve problems independently, and maintain accountability for results without compromising research ethics or protocol requirements.

Qualifications & Attributes

• Demonstrated clinical research experience with strong knowledge of clinical trial operations, GCP, protocol requirements, and data management.
• Experience recruiting or working with psychiatric, CNS, or dementia populations is strongly preferred, along with the willingness and ability to engage directly with patients with complex behavioral and cognitive needs.
• Proven ability to coordinate recruitment activities and move eligible participants efficiently through screening and randomization.
• Experience managing research staff, collaborating with recruiters, and driving measurable operational results.
• Strong working knowledge of EDC systems, source documentation, monitoring visits, query management, and audit preparation.
• Exceptional attention to detail, organizational skills, follow-through, and ability to anticipate problems.
• Excellent verbal and written communication skills, with the professionalism and confidence to engage sponsors, CROs, and monitors.
• Empathetic, patient-centered approach combined with sound judgment, resilience, and effective de-escalation skills.
• Self-motivated, accountable, adaptable, and enthusiastic about contributing to the growth of a research organization.

The Ideal Candidate

You are someone who can recruit and engage complex patients, lead recruiters, oversee randomization, maintain clean data, anticipate protocol risks, and communicate confidently with sponsors and monitors.

You don't simply identify problems—you take ownership of resolving them.

You understand that successful clinical research requires the right balance of patient empathy, recruitment performance, operational precision, regulatory compliance, and strong sponsor relationships.

You take pride in building a site that sponsors trust, monitors respect, patients feel comfortable with, and research teams are proud to represent.

Position Details

Location: West Palm Beach, Florida

Schedule: Full-Time, On-Site

Applicant Location: Currently residing in Florida

Apply through LinkedIn with your current resume.

We are looking for an engaged, growth-oriented clinical research professional who wants to make a meaningful impact on patient access to research, operational excellence, and the long-term success of our clinical research organization.

• Health Synergy Clinical Research is an equal opportunity employer.