This course is a continuation of the course on introduction to a Site Monitoring Visit. The course focus on the practical aspects of the Site Monitoring Visits and provides information on the preparation, planning, conduct and follow-up of the visit. The aim is to understand what steps should be taken to perform a perfect Site Monitoring Visit to ensure that the aim of monitoring is fulfilled. After completion of the course the participant will know and understand what the key aspects of the SMV are, how to plan the visit and obtain all necessary approval, how to prepare for the visit and which documents and materials must be reviewed. Those units are followed by the extensive unit dedicated to the SMV conduct. The main focus is on the activities to be performed and questions to be addressed. The course provides information how to follow-up the visit, which documents must be created by the CRA and how to do it. The course contains bank of questions and exercises like case study so the participant can verify the knowledge and develop skills needed to perform a Site Monitoring Visit.